IRB Barcelona is seeking a motivated scientist to join the Inflammation, Tissue Plasticity & Cancer Research Group as a Research Assistant.

The Inflammation, Tissue Plasticity & Cancer Research Group aims to understand how oncogenic mutations and inflammatory cues shape normal cellular identity and tissue homeostasis to initiate and sustain cancer. To do so, we combine functional genomics tools (CRISPR/Cas9; RNAi), mouse models and organoid/cell culture systems, and (epi)genomic methods including single-cell and spatial technologies.

The successful candidate will perform molecular/cellular biology techniques (eg. cloning, DNA/RNA/protein extractions, cell culture, genotyping) and in vivo work (eg. preclinical animal models, rodent survival surgeries, tissue/PBMC processing) to support research investigating cellular, tissue, and organismal-level determinants of epithelial carcinogenesis; and will assist in setting up and maintaining the lab’s organizational and experimental pipelines.

This position is cofinanced by the project “Unmasking Non-Genetic Determinants Instructing Tumor Initiation del European Research Council (ERC)” (Acronim: IGNITE. Grant Agreement: 101171929).

Key responsibilities

• The research technician will lead experimental and organizational activities under minimal supervision.

• Research activities may include (but are not limited to) DNA/RNA extraction, plasmid cloning, qRT-PCR, ELISA/immunoblotting, mouse handling, minor surgeries (pancreas, liver), iv/ip injections, tissue/blood processing, cell line/organoid culture, and genetic manipulation and tracing (CRISPR/RNAi, barcoding), flow cytometry and histology, preparation of lab reagents, and performing basic statistical data analysis and literature search to contribute with new ideas on topics related to the lab’s research mission.

• Operational activities may include (but are not limited to) organizing data and sample repositories, assisting team members in planning or execution of experiments; and contributing to an enriching, positive and inclusive lab environment.

You have

• Master’s degree in Biomedicine or equivalent experience.
• Experience of three years in a laboratory setting.
• Knowledge of laboratory techniques and safety protocols.
• Strong organizational and multitasking skills.
• Attention to detail and accuracy.
• Proficiency in English (both written and spoken).
• Excellent interpersonal and communication skills.
• Highly motivated and collaborative person.
• Willing to keep on learning.
• Ability to work independently in a demanding research environment.

You might also have

• Background in cancer and/or inflammation/immunology.
• Good communication and teamwork abilities.
• Experience with data analysis softwares.

What we offer:

To be a part a part of something meaningful: We are a biomedical research centre that tirelessly works to achieve a society free of diseases. Our mission is to carry out research of excellence to cure cancer and other diseases linked to ageing.

Good Working conditions: Permanent Contract (científico técnico) linked to the project “Unmasking Non-Genetic Determinants Instructing Tumor Initiation del European Research Council (ERC)”. Employed in compliance with Spanish legislation and regulations under a full-time contract. Employees receive the benefits of the Spanish Social Security system covering sickness, maternity/paternity leave and injuries at work.

Competitive salary: commensurate with experience and qualifications.

International Environment: we are home to nearly 500 researchers, technical and support staff from 45 countries.

Multidisciplinary Research: Research of excellence at the unique interface between biology, chemistry, and structural and computational biology.

Continuous Training: Transversal and general training is offered to our community (examples include research seminars, conferences, training in time management, scientific integrity, gender equality, health and safety, languages courses and emotional wellbeing).

Relocation & Visa Assistance: Trained staff provides support on visa paperwork, administrative requirements, and practical information on living and working in Barcelona, etc.

Social Life: We like to have fun. We promote several activities, like a Football League, an annual skiing trip, a Mountaineering Club, a Running Club and "Cool-off sessions", where members meet informally for drinks, snacks and scientific discussions.

Fairness: Our recruitment is open, transparent and merit-based, and all applicants compete on the same terms. We are an Equal Opportunity Employer and all qualified applicants are considered for employment without regard to race, colour, religion, age, sex, sexual orientation, gender identity, nationality, ethnic origin or disability.

HOW TO APPLY & SELECTION PROCESS:

• Deadline for applications: 01/10/2025 (If no suitable candidate is found, the deadline will be extended) 
• Number of positions available: number
• Selection process:
  • Pre-selection: Will be based on CV, motivation letter & experience.
  • Interviews: Short-listed candidates will be interviewed.
  • Job offer: Will be sent to the successful candidate after the interview. 

Note: The strengths and weaknesses of the applications will be provided upon request.