IRB Barcelona is seeking a highly motivated and talented Postdoctoral Fellow to participate in cutting edge research line -Regulation of the Retinoblastoma (RB) as a new therapeutic strategy for the treatment of cancer- of the Cell Signaling Research Group led by Dr. Francesc Posas and Dr. Eulàlia de Nadal.

Key responsabilities:

• Management and coordination of chemical compound screening as therapeutic targets, including high-throughput and/or phenotypic screens.
• Perform and optimize a variety of bioassays (biochemical, biophysical, cellular) to characterize hit compounds.
• Conduct in vivo and biochemical testing of compound activity.
• Independently design and test biological hypotheses.
• Plan, perform and interpret experiments.
• Collaborate with a multidisciplinary research team, tapping into the expertise of fellow researchers and external collaborators.
• Contribute to a culture of scientific excellence, efficiency, and teamwork.
• Contribute to other lab projects and to the maintenance of protocols and laboratory resources in the group.
• Critically analyze analytical results, participate in scientific discussions and in preparation of diverse forms of scientific communication (seminars and conferences).
• Participate in the project activities: meetings, presentations, visits to other labs, collaboration, exchange of data sets, preparing project reports/deliverables.
• Perform excellent research according to the high standards of the lab and the IRB Barcelona.

You have:

• PhD in any of the Life Sciences fields.
• Experience in the discipline of oncology.
• Experience in compound screening and characterization of chemical molecules on therapeutic targets.
• Extended knowledge in culture of mammalian cells, molecular and cell biology techniques.
• Strong peer reviewed publication record
• Demonstrated ability to design and conduct experiments independently.
• Excellent communication skills and the ability to collaborate effectively.
• Strong organizational and multitasking skills.
• Attention to detail and accuracy.
• Proficiency in English (both written and spoken).
• Highly motivated, enthusiastic and collaborative person.
• Willing to keep on learning.
• Ability to work independently in a demanding research environment.

You might also have:

• Experience with animal models of cancer and relevant certifications or a certificate of competence for handling animals for experimentation.
• Experience in high-throughput assay development using e.g. Alpha Technology.
• Research experience in signal transduction.
• Experience with mechanism of action studies and Structure-Activity Relationship analysis.
• Experience with data analysis software.

What we offer: 

• To be a part a part of something meaningful: We are a biomedical research centre that tirelessly works to achieve a society free of diseases. Our mission is to carry out research of excellence to cure cancer and other diseases linked to ageing.
• Good Working conditions:2-3 years contract as a Postdoctoral fellow. Employed in compliance with Spanish legislation and regulations under a full-time contract. Employees receive the benefits of the Spanish Social Security system covering sickness, maternity/paternity leave and injuries at work.
• Competitive salary: commensurate with experience and qualifications.
• International Environment: Nearly 90 Postdoctoral researchers (more than a half non-Spanish nationals) are currently working at IRB Barcelona.
• Multidisciplinary Research: Research of excellence at the unique interface between biology, chemistry, and structural and computational biology.
• Training and Career: Postdoctoral researchers joining IRB Barcelona gain access to the Institute’s advanced research training and career development opportunities, all within in a competitive international environment. Courses and workshops on themes of particular interest to postdocs are offered regularly by the Institute.
• Relocation & Visa Assistance: Trained staff provides support on visa paperwork, administrative requirements, and practical information on living and working in Barcelona, etc.
• Social Life: We like to have fun. We promote several activities, like a Football League, an annual skiing trip, a Mountaineering Club, a Running Club and "Cool-off sessions", where members meet informally for drinks, snacks and scientific discussions.
• Fairness: Our recruitment is open, transparent and merit-based, and all applicants compete on the same terms. We are an Equal Opportunity Employer and all qualified applicants are considered for employment without regard to race, colour, religion, age, sex, sexual orientation, gender identity, nationality, ethnic origin or disability.

HOW TO APPLY & SELECTION PROCESS:  

• Deadline for applications: 25/07/2025 (If no suitable candidate is found, the deadline will be extended) 
• Number of positions available: 1
• Selection process:
  • Pre-selection: Will be based on CV, motivation letter & experience.
  • Interviews: Short-listed candidates will be interviewed.
  • Job offer: Will be sent to the successful candidate after the interview. 

Note: The strengths and weaknesses of the applications will be provided upon request.  

About us, the institute

Created in 2005 by the Generalitat de Catalunya (Government of Catalonia) and the University of Barcelona, IRB Barcelona is a Severo Ochoa Centre of Excellence—a seal that was awarded in 2011.

The institute is devoted to conducting research of excellence in biomedicine and to transferring results to clinical practice, thus improving people’s quality of life, while simultaneously promoting the training of outstanding researchers, technology transfer, and public communication of science. Its 29 laboratories and seven core facilities address basic questions in biology and are orientated to diseases such as cancer, metastasis, Alzheimer’s, diabetes, and rare conditions.

IRB Barcelona is an international centre that hosts 500 members and 45 nationalities. It is located in the Barcelona Science Park. IRB Barcelona forms part of the Barcelona Institute of Science and Technology (BIST) and the “Xarxa de Centres de Recerca de Catalunya” (CERCA).