Created in 2005 by the Generalitat de Catalunya (Government of Catalonia) and the University of Barcelona, IRB Barcelona is a Severo Ochoa Centre of Excellence—a seal that was awarded in 2011.

The institute is devoted to conducting research of excellence in biomedicine and to transferring results to clinical practice, thus improving people’s quality of life, while simultaneously promoting the training of outstanding researchers, technology transfer, and public communication of science. Its 28 laboratories and seven core facilities address basic questions in biology and are orientated to diseases such as cancer, metastasis, Alzheimer’s, diabetes, and rare conditions.

IRB Barcelona is an international centre that hosts 400 members and 35 nationalities. It is located in the Barcelona Science Park. IRB Barcelona forms part of the Barcelona Institute of Science and Technology (BIST) and the “Xarxa de Centres de Recerca de Catalunya” (CERCA).

IRB Barcelona seeks a motivated Computational Biologist for the Quantitative Stem Cell

Dynamics Lab, led by Dr. Alejo Rodriguez-Fraticelli (fraticellilab.com).

The lab focuses on developing biotechnology to discover intrinsic regulators of stem cell heterogeneity in native hematopoiesis, leukemia and beyond.

We are looking for a candidate with a strong background in quantitative analysis, biostatistics, and genomics, and with an interest in working at the interface between epigenetic analysis and stem cell biology. The ideal candidate would also be familiar with single-cell sequencing analysis and mathematical modelling.

The Bioinformatician will be funded through the project “Mechanisms of acute myeloid leukemia therapy resistance and plasticity (AMLTRAP)” awarded by the ‘Agencia Estatal de Investigación’ in 2021.

DUTIES: 

• Carry out analyses of single-cell omics, together with other 2 Bioinformaticians (a PhD student and a Postdoc).

• Develop standardized in-house workflows to process NGS data using workflow management tools (Snakemake, Nextflow, etc).

• Collaborate with wet and dry PhD students and Postdocs in the conceptualization of new computational analyses.

• Communicate results both as group meeting presentations and as reports

• Explore new methodologies of quantitative analysis

• Participate in scientific discussions

• Write manuscripts together with other researchers

• Engage in career development activities, outreach and soft-skill training

 

EXPERIENCE, KNOWLEDGE, SKILLS & SELECTION CRITERIA

Must Have – Required

• BSc/MSc in Systems Biology, Bioinformatics, Biostatistics or other quantitative fields

• Advanced knowledge of programming for sequence analysis (Python / R / Julia)

• Knowledge in multivariable data analysis and data visualization

• Fluency in English

Desirable

• Experience in single-cell sequencing data analysis

• Experience in analysis of chromatin accessibility and immunoprecipitation

• Good understanding of statistical learning models

• Background in Developmental Biology or Cancer Biology

• Experience in international teams

• Good communication skills

 

WORKING CONDITIONS & ENTITLEMENTS: 

• Working conditions: Employed in compliance with Spanish legislation and regulations under a full-time contract. Employees receive the benefits of the Spanish Social Security system covering sickness, maternity/paternity leave and injuries at work.

• Estimated annual gross salary: Salary commensurate with experience and qualifications.

• International Environment: The opportunity to join a prestigious, diverse and inclusive international research institution and to become a member of the Quantitative Stem Cell Dynamics lab.

• Benefits: Continuous training in a high-quality environment with unique professional career opportunities.

HOW TO APPLY & SELECTION PROCESS

Applications for the above opening should include Full CV and Motivation Letter 

Deadline for applications: 01/10/2023

If no suitable candidate is found, the deadline will be extended.

• Number of positions available: 1

• Selection process:
  • Pre-selection: Will be based on CV, motivation letter & experience.
  • Interviews: Short-listed candidates will be interviewed.
  • Job Offer: Will be sent to the successful candidate after the interview.
  • Note: The strengths and weaknesses of the applications will be provided upon request.